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A surgical sealant film is an implantable
A surgical sealant film is an implantable medical device
A medical device is any device intended to be used for medical purposes. Significant potential for hazards are inherent when using a device for medical purposes and thus medical devices must be proved safe and effective with reasonable assura ...
used during surgery. It is a preformed flexible patch that is applied to supplement sutures and surgical staples
Surgical staples are specialized staples used in surgery in place of sutures to close skin wounds or connect or remove parts of the bowels or lungs. The use of staples over sutures reduces the local inflammatory response, width of the wound, a ...
to seal tissues and prevent leaks of fluid (including blood and cerebrospinal fluid
Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates.
CSF is produced by specialised ependymal cells in the choroid plexus of the ventricles of the ...
) and air.
The sealant film is synthetic and incorporates absorbable polymers, including poly(lactide-co-glycolide). The polymeric components impart structural and adhesive properties with the sealing effect achieved by incorporation of a bioadhesive polymer. This forms a covalent bond to primary amines present on the tissue surfaces. In turn this results in the film rapidly becoming effective in providing a form of secondary wound closure.
The film can be used for sealing the dura mater
In neuroanatomy, dura mater is a thick membrane made of dense irregular connective tissue that surrounds the brain and spinal cord. It is the outermost of the three layers of membrane called the meninges that protect the central nervous system. ...
, preventing blood loss in general surgery and eliminating air leaks following lung resection.
References
{{Reflist Implants (medicine)